Browse all practice questions for the Disorders of the Adrenal Gland Practice Test. Search by topic, open any question and review its full explanation, then test yourself in the practice quiz.

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  • Which feature best differentiates secondary adrenal insufficiency from primary adrenal insufficiency?
  • In a patient with suspected hyperaldosteronism, which laboratory finding would you expect?
  • Which presentation may occur in affected newborn boys with classic CAH, depending on genotype?
  • Which finding is more characteristic of primary adrenal insufficiency than secondary?
  • In Addisonian crisis, which agent is commonly administered to correct hypoglycemia and provide glucocorticoid effect?
  • Which mineralocorticoid is used for replacement in primary adrenal insufficiency and what parameter should be monitored?
  • What is the most sensitive screening approach for pheochromocytoma in pregnancy?
  • Which of the following are secondary causes of adrenal insufficiency?
  • When caring for a patient with hypercortisolism, the nurse begins to feel the onset of symptoms of a cold but still has 4 hours left in the shift. Which action by the nurse is correct?
  • Which hormones are primarily produced by the adrenal cortex?
  • In primary hyperaldosteronism, how does the RAAS respond and what is the expected renin level?
  • Which preventive measure is recommended for patients on chronic glucocorticoids?
  • Which statement best describes Cushing disease?
  • What is the recommended perioperative pharmacologic approach to pheochromocytoma?
  • In acute primary adrenal insufficiency, which electrolyte pattern is typical?
  • What electrolyte abnormality is commonly seen with hypoaldosteronism?
  • Which imaging feature is considered suspicious for an adrenal incidentaloma?
  • After educating a patient with hypercortisolism about preventing injury, which statement indicates effective understanding?
  • Which assessment finding is consistent with a diagnosis of hyperaldosteronism?
  • How does ACTH influence adrenal cortex zones?
  • Which intervention would the nurse delegate to the AP who is providing care to a patient with Cushing disease?
  • Secondary adrenal insufficiency is most commonly due to which etiology?
  • What MRI finding is often seen in pheochromocytoma on T2-weighted imaging?
  • In the metyrapone test, what results indicate a normal HPA axis compared with a deficient axis?
  • Besides increased cortisol, which laboratory result would you expect in a patient with suspected Cushing disease?
  • During initial evaluation for pheochromocytoma, which test is used to screen for catecholamine metabolites?
  • Which laboratory value would be most consistent with a diagnosis of adrenal insufficiency?
  • Which of the following is a priority question in assessing a patient with suspected adrenal crisis due to corticosteroid withdrawal?
  • Which laboratory values should be monitored in a patient with adrenal hypofunction receiving steroid replacement?
  • What is the most common cause of primary adrenal insufficiency in developed countries?
  • Autoimmune adrenalitis is the most common cause of primary adrenal insufficiency in developed countries. It destroys which tissue of the adrenal gland?
  • Which manifestation would the nurse anticipate finding in a patient diagnosed with adrenal insufficiency?
  • Which biochemical profile favors a diagnosis of primary aldosteronism over secondary hypertension?
  • Recognizing that a patient with Cushing disease is at risk for injury, which intervention would the nurse include in the patient's plan of care?
  • Which medication is contraindicated for a patient diagnosed with acute adrenal insufficiency and hyperkalemia?
  • Which statement best reflects awareness of hydrocortisone adverse effects in glucocorticoid deficiency management?
  • Which finding would the nurse expect to see in a patient with hyperaldosteronism?
  • Which condition is commonly managed with adrenalectomy?
  • What skin finding is commonly associated with chronic adrenal insufficiency?
  • In a patient experiencing an Addisonian crisis with laboratory results showing potassium 5.4, sodium 130, calcium 8.0, and blood glucose 70, which medication would the nurse anticipate administering?
  • Which patient should be assessed first when considering hypertensive crisis and tremors in a Conn syndrome patient?
  • Assessment findings of moonface, hypertension, petechiae, and truncal obesity indicate increased ACTH. Which medication does the nurse expect to be prescribed?
  • Which physical finding is most characteristic of hypercortisolism?
  • Which medication is used for treatment of Cushing disease?
  • Which treatment modality would the health care provider prescribe for a patient with hyperaldosteronism?
  • Which adrenal gland cell type secretes catecholamines and what is the typical proportion of epinephrine to norepinephrine?
  • In patients with renal impairment, which screening test is preferable for pheochromocytoma and why?
  • A patient presents with symptoms consistent with acute adrenal insufficiency. Vital signs show a pulse of 118, respiratory rate 18, blood pressure 84/44, oxygen saturation 98%, and a temperature of 98.8 F. What is the priority intervention?
  • In classic CAH due to 21-hydroxylase deficiency, which combination of hormone production occurs?
  • Why should beta-blockade be used cautiously in pheochromocytoma?
  • Which genetic syndromes are associated with pheochromocytoma?
  • For planning care of a patient with acute adrenal insufficiency, which hormone deficit guides the interventions?
  • ACTH has what effect on aldosterone production?
  • Which electrolyte abnormality is typical in primary adrenal insufficiency?
  • Which manifestation would the nurse anticipate finding in a patient diagnosed with Cushing disease?
  • A patient with Cushing disease has fragile skin; which shaving aid is appropriate to minimize injury?
  • Which manifestation would the nurse expect to find in a patient with Cushing disease?
  • Which electrolyte change may accompany an acute primary adrenal crisis due to low cortisol?
  • Which question by the nurse is a priority when a patient on long-term corticosteroid treatment reports fatigue, nausea, and salt cravings?
  • Which parameter is elevated in a patient with adrenal insufficiency?
  • Which statement best explains emotional changes in Cushing disease?
  • To allow for appropriate dose adjustments, which instruction would you provide to a patient prescribed oral hydrocortisone for adrenal insufficiency?
  • Metyrapone test measures which hormone after administration to assess the HPA axis?
  • What ARR threshold and aldosterone level are commonly used to screen for primary hyperaldosteronism?
  • If a high-dose dexamethasone suppression test results in cortisol suppression, which source of ACTH is more likely?
  • Which condition would be least likely to cause adrenal insufficiency?
  • In metyrapone testing, what indicates an intact hypothalamic-pituitary-adrenal axis?
  • Which medication would be prescribed for ACTH-mediated Cushingoid features (e.g., moonface) as described in the scenario?
  • In a patient with adrenal gland hypofunction, which electrolyte abnormality should the nurse monitor for?
  • How does CAH typically present in a newborn girl versus a boy?
  • Which assessment finding would indicate infection in a patient who underwent an adrenalectomy?
  • Which history item is least relevant when evaluating a female patient for suspected adrenal hypofunction?
  • A serum cortisol level of 4 mcg/dL suggests which condition?
  • What is essential preoperative management for pheochromocytoma and why?
  • After confirming a pheochromocytoma, what are the essential next steps before surgical resection?
  • Which action would the nurse take first when a patient with Cushing disease reports a weight loss of 5lbs?
  • Which statement best describes the adrenal function finding in Addisonian crisis?
  • Which combination of electrolyte abnormalities is most typical in adrenal insufficiency?
  • After a shift handoff about four patients, which patient would the nurse attend to first?
  • Which change would the nurse expect to find in a patient with hypercortisolism upon physical assessment?
  • What infection-control measure is appropriate when caring for a patient with hypercortisolism who develops a cold during care?
  • Which laboratory tests would likely be ordered for a patient with acute adrenal insufficiency?
  • Which combination of signs is commonly seen in Cushing disease?
  • Which medication blocks cortisol receptors and is used in Cushing syndrome when surgical options are limited?
  • Which enzyme deficiency underlies most cases of congenital adrenal hyperplasia and what hormone pathway is affected?
  • What is the initial management step in suspected adrenal crisis?
  • Which is a common cause of secondary adrenal insufficiency?
  • Which test is used in the initial hormonal workup to screen for cortisol excess in adrenal incidentaloma evaluation?
  • Which patient should be prioritized for assessment when managing adrenal-related conditions, including Cushing disease and possible adrenalectomy?
  • Why is metyrapone generally avoided in pregnancy?
  • Under what circumstances is adrenal venous sampling most indicated in suspected unilateral hyperaldosteronism?
  • Which type of cortisol response would the nurse expect when a patient with secondary adrenal insufficiency undergoes an adrenocorticotropic hormone stimulation test?
  • Which disorder causes the adrenal cortex to secrete too much cortisol?
  • What is a nursing priority for a patient presenting to the ED with a history of adrenal insufficiency and laboratory results showing Na 130, K 5.6, and glucose 72?
  • Which electrolyte abnormality is typical in adrenal insufficiency?
  • Which is a primary cause of adrenal insufficiency?
  • Which sign is most specific for an adrenal source of androgen excess in a female?
  • Which medication instruction would the nurse provide to a patient who is prescribed cortisone for treatment of hypofunction of the adrenal gland?
  • Which clinical finding would the nurse expect in a patient with reduced aldosterone secretion?
  • Which instruction is correct for a patient taking cortisone for adrenal hypofunction?
  • Following unilateral adrenalectomy, what is the expected status of adrenal function?
  • Which imaging modality is commonly used to localize pheochromocytoma after biochemical confirmation?
  • What imaging study is typically used first to evaluate an adrenal incidentaloma?
  • Which is the nurse's best response when a patient with Cushing disease begins to laugh loudly and inappropriately, causing the family in the room to be uncomfortable?
  • A patient suspected of having Cushing disease is scheduled for dexamethasone suppression testing. Which statement indicates need for further teaching?
  • In a patient being evaluated for Cushing disease, which lab pattern would most strongly indicate the disease when considered with cortisol?
  • After reviewing laboratory reports for a patient with hypercortisolism, which finding should be reported immediately to the primary care provider?
  • Which hormone is primarily a mineralocorticoid?
  • Which class of medications is used to treat Cushing syndrome when surgery isn’t possible?
  • The rationale for divided prednisone dosing in adrenal insufficiency is to mimic what physiological pattern?
  • What testing modality is preferred for diagnosing pheochromocytoma?
  • Which skin change would the nurse expect to find in a patient with hypercortisolism?
  • In screening for pheochromocytoma, which statement about plasma-free metanephrines is true?
  • Which constellation of features is most consistent with Cushing syndrome due to ACTH excess?
  • Which intervention would the nurse include in a plan of care that addresses the risk for infection in a patient who is immobile and immunosuppressed because of hypercortisolism?
  • How should glucocorticoid replacement be dosed to mimic normal physiology in Addison's disease?
  • Which electrolyte abnormality occurs in adrenal insufficiency?
  • Which is an important nursing assessment for a patient receiving fludrocortisone to treat adrenal hypofunction?
  • Which is a common side effect of spironolactone therapy for hyperaldosteronism?
  • If a patient has hypercortisolism and edema, which electrolyte change is commonly observed?
  • Which condition is associated with osteoporosis as a musculoskeletal complication?
  • Which test helps differentiate pituitary from ectopic ACTH production in suspected Cushing syndrome?
  • In primary aldosteronism, what are the expected laboratory findings?
  • Which action by a patient with hypercortisolism can help prevent GI bleeding?
  • How can primary adrenal insufficiency be differentiated from secondary adrenal insufficiency using ACTH and cortisol levels?
  • Which laboratory finding is most consistent with a diagnosis of Cushing disease?
  • What is the first-line imaging modality and suspicious features for evaluating an adrenal incidentaloma?
  • Which clinical manifestation would the nurse expect to find in a patient with hyperaldosteronism?
  • In the management of adrenal disorders, which parameter should be monitored to assess the effectiveness of fludrocortisone therapy?
  • Which nursing intervention is appropriate for a patient diagnosed with adrenal hypofunction?
  • Which patient should be assessed first among those with adrenal hypofunction?
  • Which immune change is associated with infection risk in hypercortisolism?
  • After a positive biochemical test for pheochromocytoma, what is the next recommended step?
  • Which condition is included in the differential diagnosis of an adrenal incidentaloma?
  • What is the classic triad of symptoms for pheochromocytoma?
  • After providing education to a patient who is scheduled for a unilateral adrenalectomy, the nurse identifies that which statement by the patient indicates that the teaching was effective?
  • Which medication would the nurse plan to administer to a patient diagnosed with hyperaldosteronism?
  • After reviewing inpatient assignments, which patient should be assessed first?
  • What is the initial fluid resuscitation choice in suspected acute adrenal crisis?
  • Distinguish Cushing disease from Cushing syndrome.
  • What safety measure should the nurse use when assisting a patient with hypercortisolism who is at risk for bone fractures?
  • What is the rationale for administering ranitidine to a patient who is experiencing acute adrenal insufficiency?
  • How can untreated CAH affect growth and puberty?
  • Which medication is used to treat Cushing disease?
  • Which instruction would be appropriate to delegate to assistive personnel for a hospitalized patient with suspected Cushing disease?
  • For a patient with adrenal insufficiency starting a cortisol replacement, which instruction should the nurse include in patient education?
  • Which instruction reflects appropriate divided dosing of prednisone for adrenal hypofunction?
  • What is the purpose of the low-dose and high-dose dexamethasone suppression tests in the evaluation of suspected Cushing's syndrome?
  • Which combination of findings would most support a diagnosis of Cushing disease?
  • The nurse instructs a patient who is taking fludrocortisone for adrenal hypofunction to report which symptom to the health care provider?
  • Waterhouse-Friderichsen syndrome is most accurately described as?
  • List common clinical features of Cushing syndrome.
  • Why might a separate mineralocorticoid be required in the management of Addison's disease?
  • Which baseline morning cortisol value would prompt ACTH stimulation testing for suspected adrenal insufficiency?
  • How do chronic exogenous glucocorticoids lead to Cushingoid features?
  • Describe Addisonian crisis presentation?
  • What is a nursing priority for a hospitalized patient with Cushing disease?
  • Which teaching specific to hydrocortisone would the nurse provide to a patient who is prescribed the medication to treat glucocorticoid deficiency?
  • During a cosyntropin stimulation test, what constitutes an inadequate cortisol response?
  • Which musculoskeletal problem is associated with Cushing disease?
  • Which discharge instruction is essential for a patient taking exogenous glucocorticoids to treat hypercortisolism?
  • In unilateral suspected hyperaldosteronism, why is adrenal venous sampling used?
  • In a patient with hypercortisolism, which finding would contribute to the potential for infection?
  • Which medication is used to treat hyperaldosteronism?
  • Which laboratory finding is consistent with hyperaldosteronism?
  • Which of the following statements about differentiating pituitary versus ectopic ACTH production is true?
  • Which clinical finding would the nurse expect to find in a patient with Cushing disease?
  • Which laboratory test would be expected for a patient admitted with acute adrenal insufficiency?
  • Which patient should be assessed first given electrolyte abnormalities suggestive of adrenal insufficiency?
  • In the ED, a patient presents with hypertension, fatigue, and a 3-day history of weight loss and vomiting. A crisis is suspected. Which question is a priority?
  • If noncontrast CT is indeterminate for an adrenal incidentaloma, what imaging is typically used next for further characterization?
  • For which reason would telemetry monitoring be indicated for a patient with acute adrenal insufficiency?
  • Cushing disease commonly causes which metabolic abnormality?
  • What is a common cause of secondary adrenal insufficiency?
  • In a patient with reduced aldosterone secretion, which electrolyte abnormality would you expect?
  • What signs may indicate an adrenal source of androgen excess in a female patient?
  • When assigning patients, which scenario would justify giving the patient to an RN floated from the pediatric unit?
  • Which electrolyte abnormalities are typical in primary adrenal insufficiency?
  • What is the purpose of the cosyntropin (ACTH) stimulation test and how is its result interpreted?
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